Introduction. Balanoposthitis is one of the most common and widespread uroandrological problems in children. In pediatrics, as a rule, the treatment of the disease is conservative. Surgical aid is required in rare rare cases.
Objective: to scientifically substantiate the clinical efficacy of the Balanex® Kids cream-gel in various forms of balanoposthitis in children, as well as to compare the original product with traditional therapy methods.
Materials and Methods. An open prospective randomized study was conducted involving 20 patients aged 4-12 years. Participants were di- vided into 4 groups: a control group (healthy children) and three clinical groups with various forms of balanoposthitis (acute purulent, acute catarrhal, chronic). Within the groups, patients received different therapies: Balanex® Kids locally on the inflammation area (glans penis, fore- skin) or the standard treatment – sanitation of the preputial sac with chlorhexidine solution and a local combined agent with an antibacterial agent (chloramphenicol + dioxomethyltetrahydropyrimidine). The assessment was based on clinical parameters and expanded microbiological parameters obtained as a result of mass spectrometric analysis of the bacterial mass of the urogenital tract according to Osipov.
Results. The dynamics of clinical improvement varied significantly among all study groups. In acute purulent balanoposthitis, standard therapy showed more pronounced positive dynamics. Balanex® Kids demonstrated higher efficacy in catarrhal and especially chronic forms. Clinical results were supported by microbiological research data.
Conclusions. The obtained results substantiate a personalized approach to the treatment of balanoposthitis in children, taking into account the nosological form and microbiological status. Balanex® Kids s optimal for use in catarrhal forms of balanoposthitis, both acute and chronic.

